Update on small intestinal stem cells

Mesenchymal stem cells in osteoarticular diseases: an update

Multipotent mesenchymal stromal cells or mesenchymal stem cells (MSCs) are mainly isolated from bone marrow or fat tissue. Because of their potential of multilineage differentiation towards bone, cartilage and fat tissue, they were initially evaluated to develop innovative strategies for tissue engineering applications. More recently, they have gained interest based on their immunomodulatory pr...

Small Intestinal Transplantation: An Update

Organ transplantation is indeed a revolution in management of end-stage organ failure. The one year graft survival rates for solid organs now routinely exceed 85 per cent for the kidney, liver and heart. The enhanced success rate is due to better immunosuppression, improvement in surgical techniques, organ preservation and better understanding of the immunology of rejection. The small intestine...

Update on Small Intestinal Bacterial Overgrowth and Antibiotic-responsive Diarrhea

Gastrointestinal stem cells. II. Intestinal stem cells.

Current views of the identity, distribution, and regulation of small intestinal epithelial stem cells and their immediate progeny are discussed. Recent works implicating Wnt signaling in stem and progenitor proliferation, the involvement of Notch signaling in epithelial lineage specification, and the role of hedgehog and bone morphogenetic protein families in crypt formation are integrated. We ...

Putative intestinal stem cells

A heterogeneous set of intestinal stem cells markers has been described in intestinal glands but the ultrastructural identity of intestinal stem cells remains unknown. By using electron microscopy, this study demonstrated the presence of cells with stem morphology in the intestinal glands of mice of different ages. These putative intestinal stem cells have large, euchromatic, irregular shaped n...